Proteomic Screening Applied To Early The Diagnosis Of Chronic Graft-Versus-Host-Disease
نویسندگان
چکیده
منابع مشابه
Chronic graft-versus-host disease.
Mr. F is a 62-year-old Caucasian man who was diagnosed with acute myelogenous leukemia (AML) 15 months prior. Following two cycles of induction chemotherapy, his AML was in remission. Four months ago, after a reduced-intensity conditioning regimen, Mr. F received an allogeneic peripheral blood stem cell transplant from his human leukocyte antigen–identical 56year-old sister. Mr. F received a re...
متن کاملDiagnosis and management of chronic graft-versus-host disease.
A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of chronic graft-versus-host disease (GvHD). This guideline includes recommendations for the diagnosis and st...
متن کاملManagement of chronic graft-versus-host disease.
Chronic graft-versus-host disease (GVHD) is an immune-mediated disorder that adversely affects quality of life and clinical outcomes in patients following hematopoietic stem cell transplantation. Conventional treatment of GVHD includes prolonged and high-dose corticosteroids; however, those drugs are associated with multiple side effects. This article describes the ability of extracorporeal pho...
متن کاملProgress in chronic graft-versus-host disease
255 PRF deficiency occurs not only with allelic variants characterized by mutations in the coding region of the gene. McIlroy et al. reported that the occurrence of a C/T polymorphism at position-398 of the proximal promoter region of the PRF1 gene was associated with decreased quantities of PRF in CTLs in HIV infected patients. A decrease of about 50% of control PRF levels was observed in hete...
متن کاملChronic polyarthritis and graft-versus-host disease.
SIR—In previous studies, the presence of arthralgias and transitory arthritis in graft-versus-host disease (GVHD) has been reported, but not chronic arthritis. We will consider a case of non-erosive polyarthritis after a bone marrow transplantation in the context of chronic GVHD. A 32-yr-old male was diagnosed at the age of 27 as having acute myeloblastic leukosis. One year after the diagnosis,...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2010
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2009.12.060